Adaptation to Environmental Stimuli within the Host: Two-Component Signal Transduction Systems of Mycobacterium tuberculosis
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چکیده
منابع مشابه
Adaptation to environmental stimuli within the host: two-component signal transduction systems of Mycobacterium tuberculosis.
Pathogenic microorganisms encounter a variety of environmental stresses following infection of their respective hosts. Mycobacterium tuberculosis, the etiological agent of tuberculosis, is an unusual bacterial pathogen in that it is able to establish lifelong infections in individuals within granulomatous lesions that are formed following a productive immune response. Adaptation to this highly ...
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The bacterial two-component signal transduction systems regulate adaptation processes and are likely to play a role in Mycobacterium tuberculosis physiology and pathogenesis. The previous initial characterization of an M. tuberculosis response regulator from one of these systems, mtrA-mtrB, suggested its transcriptional activation during infection of phagocytic cells. In this work, we further c...
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ژورنال
عنوان ژورنال: Microbiology and Molecular Biology Reviews
سال: 2011
ISSN: 1092-2172,1098-5557
DOI: 10.1128/mmbr.05004-11